To answer your question: Definitely.
I can remember countless times when I found something related to my life and mindset somehow making its way into what Im drawing or animating.
Eammy does have a point too, if you don't have the skill to do something, your style will most likely avoid it. If you don't have the time to do something, the style you choose to use will probably find a way around it.
For my latest project I chose a simple style because of time restraints, but I didn't hold back on the amount of content or the quality of the content.. just the style makes it easier to mass produce in good quality, while avoiding time consuming nuances like lip synch and proper anatomy.
I-smel
Keep an eye out for Intrusion 2, and remind yourself that you actually don't fucking know how to use Flash at all.
<a href="http://www.youtube.com/watch?v=BJZAzNKZBew">www.youtube.com/watch?v=BJZAzNKZBew</a>